Uncovering Structural Insights into GPCR Activation & Drug Design with Cryo-EM

Time: 12:00 pm
day: Day One

Details:

• How to successfully capture ligand-receptor structural affinity complexes with higher resolution for structure-based drug discovery and design
• How to detect a dynamic range of GPCR activation and conformation with protein binding transitions using Cryo-EM technology for lead optimization
• Deciphering the homology of ligand binding pocket structures to improve drug fusion characteristics