Steven Wolk

Company: Editas Medicine

Job title: Vice President & Head of Chemistry & Boulder Site

Seminars:

Update on the Development of Standardized mRNA/LNP CQAs for Therapeutic Applications 2:00 pm

Current state of existing regulatory guidance Review of the proposed list of CQAs, and analytical methods Areas for additional development CRISPR-specific considerationsRead more

day: Conference Day Two

Roundtable Discussion: Innovations in Addressing Purification Challenges to Produce High Quality mRNA Therapeutics & Vaccines 11:00 am

What the best methods for mRNA purification?  Do they change with scale?  Does a two-step purification significantly improve purity? Under what circumstances (volume, throughput) do the continuous purification methods offer significant advantage? For dsRNA: What are the best approaches to reduce dsRNA during IVT Which forms are dominant and which forms are immunogenic What are…Read more

day: Conference Day One